GABA Receptor Research and The Power of Probiotics

The Connection Between GABA and Probiotics

“Probiotics are living microorganisms that, when administered in adequate amounts, confer a benefit to the health of the host.” (SOURCE)

Probiotics can be found in food or taken as a supplement. One benefit of choosing to supplement with a probiotic is that specific species and strains can be targeted to help with specific issues; for example mood support.

Exciting research in the field of the gut-brain connection suggests that specific types of probiotic bacteria may help regulate the nervous system by modulating the activity of various neurotransmitter receptors, including GABA receptors. (SOURCE)

GABA (gamma-aminobutyric acid) is a neurotransmitter that plays a key role in regulating stress levels. According to the above study, one mechanism by which probiotics may help to reduce stress is by modulating the activity of GABA receptors.

Administration of Lactobacillus Rhamnosus for Mood

In the above stated study, it was discovered “…that chronic treatment with L. rhamnosus (JB-1) induced region-dependent alterations in GABAB1b mRNA in the brain with increases in cortical regions (cingulate and prelimbic) and concomitant reductions in expression in the hippocampus, amygdala, and locus coeruleus, in comparison with control-fed mice.” (SOURCE)

While there are numerous neurotransmitters at play when it comes to the gut-brain connection, this type of research involving GABA production and stress levels in the body is gaining traction in the field of microbiota and mood support. And, yes, this specific strain is used in our proprietary formula, Mood Boosting Probiotic.

Another clever research article titled “May the Force Be With You: The Light and Dark Sides of the Microbiota–Gut–Brain Axis in Neuropsychiatry,“ shared about the gut-brain connection as a mystical force, stating: “The gut microbiota, like the Force, give us power.” (SOURCE)

Now, that’s food for thought.